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KMID : 0191120110260111508
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Journal of Korean Medical Science
2011 Volume.26 No. 11 p.1508 ~ p.1511
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Plexiform Angiomyxoid Myofibroblastic Tumor of the Stomach: A Case Report
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Kim Ae-Ri
Bae Young-Kyung
Shin Hyeong-Chan
Choi Joon-Hyuk
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Abstract
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Plexiform angiomyxoid myofibroblastic tumor (PAMT) is a recently described mesenchymal tumor of the stomach. We report the first case of PAMT in Korea. A 52-yr-old man underwent esophagogastroduodenoscopy due to dyspepsia for 2 yr. There was a submucosal mass with small mucosal ulceration in the gastric antrum. The tumor measured 3.5 × 2.3 cm in size and showed multinodular plexiform growth pattern of bland-looking spindle cells separated by an abundant myxoid or fibromyxoid matrix rich in small thin-walled blood vessels. The tumor cells were negative for CD117 (c-KIT), CD34 and S-100 protein, but diffusely positive for smooth muscle actin consistent with predominant myofibroblastic differentiation. The patient is doing well without recurrence or metastasis for 5 months after surgery. Although there have been limited follow-up data, PAMT is regarded as a benign gastric neoplasm with histological and immunohistochemical charateristics distinguished from gastrointestinal stromal tumor and other mesenchymal tumors of the stomach.
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KEYWORD
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Plexiform Angiomyxoid Myofibroblastic Tumor, Stomach, Myofibroblast, Fibromyxoma, Plexiform
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